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TB 500 & BPC 157 10 mg Mix

Original price was: 84,99 €.Current price is: 54,99 €. with VAT

A premixed stack of 5 mg BPC-157 + 5 mg TB-500 in a single vial. BPC-157 acts locally via the FAK-paxillin pathway, while TB-500 acts systemically by binding to actin—this combination is currently being studied for its complementary regenerative mechanisms. Fewer reconstitutions, an exact 1:1 ratio, and fewer vials in the protocol.

Purity of each component ≥ 98% – HPLC prior to premixing, COA available upon request
10 mg of lyophilized powder (5 + 5 mg), −20 °C | 2–8 °C for up to 30 days after reconstitution
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Quantity	Price	% Discount
7+	49,49 €	10%
4+	52,24 €	5%

All products are sold exclusively for the purpose of scientific research and development.
The chemical substances may not be used as a medicine, drug, active substance, medical device, cosmetic product, substance for the manufacture of a cosmetic product, or as a substance for human consumption, i.e. as a food or nutritional supplement, or in any other similar way on humans or animals.

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Description

TB-500 & BPC-157 10 mg Mix – Pre-mixed Stack for Regeneration Research

⚠️ Warning: This product is intended solely for scientific research purposes (research use only). It is not intended for use as a medicine, drug, dietary supplement, or for human use. Sale restricted to individuals over the age of 18.
The TB-500 & BPC-157 Mix is a premixed research compound containing 5 mg of BPC-157 and 5 mg of TB-500 in a single lyophilized vial (total weight 10 mg). This stack was designed for researchers investigating the synergistic effects of both peptides and seeking simpler sample preparation for laboratory work. Both peptides are individually the subject of extensive preclinical research; the combination is the subject of studies on complementary regenerative mechanisms. On jacked.sk, the TB-500 & BPC-157 Mix is available exclusively for scientific research purposes.

What is the TB-500 & BPC-157 Mix?

Ingredients: 5 mg BPC-157 + 5 mg TB-500 in one vial

The mix contains precisely measured amounts of two different research peptides:

BPC-157 (Body Protection Compound 157) – a synthetic pentadecapeptide (15 amino acids) isolated from human gastric juice; purity of each component ≥98%
TB-500 (Thymosin Beta-4) – a synthetic version of a 43-amino acid endogenous peptide; purity of each component ≥98%

Each ingredient is individually tested using HPLC before premixing, which ensures the accuracy of the declared composition.

Why a premixed stack? Benefits for research

For researchers who routinely work with both peptides, the premixed stack offers several practical advantages: a reduction in the number of reconstitutions, precise 1:1 ratio dosing, fewer vials, and logistical simplicity in preparing laboratory protocols. Researchers who need variable component ratios may prefer to purchase individual peptides separately.

The Scientific Basis of the Combination: Complementary Mechanisms

Scientific interest in the combination of BPC-157 and TB-500 is based on the assumption that both peptides act through distinct but potentially synergistic mechanisms at different levels of the biological response to injury.

BPC-157 – Local Regeneration Axis (FAK-paxillin / NO Synthase)

BPC-157 acts primarily through the FAK-paxillin (focal adhesion kinase) and NO synthase (nitric oxide synthase) signaling pathway. Research in animal models has observed its effect on wound and tissue healing in the immediate vicinity of the lesion—therefore, the effects of BPC-157 are described in the literature as local and targeted. BPC-157 is a fragment of the BPC protein isolated from human gastric juice and has demonstrated stability in the acidic environment of the stomach in preclinical models.

TB-500 – Systemic Regeneration Axis (Actin Mechanism)

TB-500 acts by binding to G-actin via the LKKTETQ sequence, thereby regulating the polymerization of actin filaments. This mechanism has a much broader, systemic nature —it influences cell migration, angiogenesis, and the tissue response to injury throughout the body. Thymosin Beta-4 is naturally present in platelets, suggesting a role in the systemic coordination of repair processes.

Preclinical Research on Combined Administration

In studies using rat models, the combined administration of BPC-157 and TB-500 was investigated in various types of tissue injuries. Preclinical data suggest that the local effect of BPC-157 and the systemic effect of TB-500 are complementary—a hypothesis that underpins the research interest in this combination. These results are preclinical and do not indicate effects in humans.

Overview of Research Areas for the Combination of BPC-157 and TB-500

Tendons and Ligaments

Preclinical research using animal models examined the effect of a combination of BPC-157 and TB-500 on tendon (Achilles tendon) and ligament (anterior cruciate ligaments) injuries. The research observed accelerated histological healing and improved mechanical properties of the regenerated tissues compared to the control groups. (Hsieh MJ et al., studies in rat models)

Gastrointestinal tract

BPC-157 has been particularly well studied in preclinical models in the context of the GI tract—its gastroprotective and ulcer-protective properties are among the most extensively documented areas of research on this peptide. TB-500 complements this mechanism by influencing angiogenesis in the GI tract mucosa. Combined research using models of inflammatory bowel disease (IBD) is an active area of study.

The Heart Muscle and the Circulatory System

Both peptides have a documented effect on the cardiovascular system in preclinical models: TB-500 through the migration of cardiomyocyte progenitors and the reduction of apoptosis following ischemic injury, and BPC-157 through NO-dependent angiogenesis and vascular protection. The combined study is investigating whether these effects are additive or synergistic.

Mixtures vs. Individual Compounds – When to Use Which in Research

Situation	Recommendations for Research
Research on the synergistic effect of both peptides in a 1:1 ratio	TB-500 & BPC-157 Mix 10 mg
Research requiring a variable ratio of BPC-157 to TB-500	Individual products (BPC-157 5 mg + TB-500 5 mg)
Research on the Mechanism of Action of BPC-157 Alone	BPC-157 5 mg alone
Research on the Mechanism of Action of TB-500 Alone	TB-500 5 mg alone
Pilot study using a standard 1:1 protocol	Mix – Simpler Logistics

Product Technical Specifications

Parameter	Value
Ingredients	5 mg BPC-157 + 5 mg TB-500
Total weight	10 mg
Form	Freeze-dried powder (lyophilisate)
Purity of each component	≥98% (HPLC-verified)
Storage	−20 °C (long-term); 2–8 °C (after reconstitution, up to 30 days)
Intended Use	For scientific research purposes only

Storage and Reconstitution for Research Use

The lyophilized mixture is stable at −20 °C in its original, sealed packaging. For reconstitution in laboratory research, bacteriostatic water for injection or sterile water is used—the same principles apply to the premixed product as to the individual peptides. After reconstitution, the product is stable at 2–8 °C for 30 days. Repeated freezing reduces the integrity of both peptide components—therefore, aliquoting is recommended before the first freezing.

Frequently Asked Questions About the TB-500 & BPC-157 Mix (FAQ)

What is in the TB-500 & BPC-157 Mix?

The TB-500 & BPC-157 blend contains 5 mg of BPC-157 (Body Protection Compound 157, a 15-amino acid peptide) and 5 mg of TB-500 (synthetic Thymosin Beta-4, 43 amino acids) in a single lyophilized vial with a total weight of 10 mg. The purity of each component is ≥98%, as verified by HPLC analysis. This product is intended exclusively for scientific research purposes.

Why do researchers combine TB-500 with BPC-157?

Scientific interest in this combination stems from the complementary nature of the mechanisms: BPC-157 acts locally via the FAK-paxillin signaling pathway and NO synthase, while TB-500 acts systemically via the actin mechanism. Preclinical research in animal models suggests that these mechanisms complement each other in various types of tissue injuries—tendons, ligaments, the GI tract, and the heart muscle. The combination is the subject of active preclinical research.

Does it make sense to buy a blend instead of individual peptides?

For researchers working with a fixed 1:1 protocol (equal amounts of both peptides), the premixed product is more convenient—it reduces the number of reconstitutions, simplifies logistics, and ensures precise proportional dosing. For research requiring a variable ratio of components (such as 2:1 or 1:2), it is more suitable to purchase the individual peptides separately.

What is the purity of each ingredient in the mix?

The purity of each component (both BPC-157 and TB-500) is ≥98%, as verified by HPLC (high-performance liquid chromatography) prior to premixing. A Certificate of Analysis (CoA) is available for each batch. The CoA includes the molecular identification, percentage purity, and analytical method results.

How should Mix TB-500 & BPC-157 be stored and reconstituted?

Store the lyophilized mixture at −20 °C in its original, sealed container (stable for 24 months). Use bacteriostatic water for injection for reconstitution (the standard volume depends on the desired experimental concentration). After reconstitution, store at 2–8 °C and use within 30 days. Protect the product from light and repeated freezing.

Is it better to use a mix or individual peptides in research?

It depends on the research protocol. The mix is more practical when using a fixed 1:1 ratio and a standard research protocol. Individual peptides are more suitable when the research requires different dosages of each component, when you want to monitor the effect of each peptide in isolation, or when you need a larger amount of one of the components. Both approaches are valid in scientific research.

⚠️ Warning – Intended exclusively for research purposes

All products sold on jacked.sk are intended EXCLUSIVELY for scientific research purposes. They are not intended for use as a medicine, drug, dietary supplement, or cosmetic product, nor for human or veterinary use. The results cited in the descriptions are based on preclinical studies (in vitro, animal models) and cannot be automatically extrapolated to human use. Sale restricted to individuals over the age of 18. By purchasing this product, the customer confirms that they are a professional researcher and will use the product solely in accordance with applicable laws.