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Selank 10 mg

Original price was: 32,99 €.Current price is: 21,99 €. with VAT

Selank is a synthetic heptapeptide—a stabilized analogue of the endogenous immunomodulator Tuftsin—developed at the Russian Academy of Sciences. Research on Selank focuses on the modulation of the GABAergic system, the inhibition of enkephalinases, and its effects on memory and cognitive functions.

Purity ≥ 98% – Each batch verified by HPLC; COA available upon request
10 mg of lyophilized powder, store at −20 °C
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Quantity	Price	% Discount
7+	19,79 €	10%
4+	20,89 €	5%

Categories: Research on Cognitive Functions, Sleep Research Tag: Selank

All products are sold exclusively for the purpose of scientific research and development.
The chemical substances may not be used as a medicine, drug, active substance, medical device, cosmetic product, substance for the manufacture of a cosmetic product, or as a substance for human consumption, i.e. as a food or nutritional supplement, or in any other similar way on humans or animals.

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Description

H1: Selank 10 mg – Anxiolytic Heptapeptide for Neuroscience Research

⚠️ Warning: Selank sold on jacked.sk is intended exclusively for scientific research purposes (research use only). It is not intended for human use; it is not a drug, dietary supplement, or cosmetic product. Intended only for qualified researchers.

What is Selank? Origin and Scientific Basis

Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It was designed as a stabilized analog of the endogenous immunomodulator Tuftsin (Thr-Lys-Pro-Arg), to which a Pro-Gly-Pro extension was added—the same approach used in the development of Semax. This extension increases the peptide’s metabolic resistance to enzymatic degradation.
Selank was developed in collaboration between the Institute of Molecular Genetics of the RAS (Russian Academy of Sciences) and the Institute of Higher Nervous Activity and Neurophysiology of the RAS in Moscow. It has been registered in the Russian Federation as an anxiolytic—however, this approval does not apply in European Union countries or the United States. In the international research community, Selank is classified as a neuropeptide with an anxiolytic and nootropic profile currently under investigation.

Chemical Structure and Properties

Parameter	Value
Sequence	Thr-Lys-Pro-Arg-Pro-Gly-Pro
Class	Synthetic heptapeptide, Tuftsin analog
Molecular weight	863.0 Da
Form (jacked.sk)	10 mg freeze-dried powder
Purity	≥98% (HPLC-verified)
Storage	−20 °C; protect from light and moisture
Administration in Research	Intranasal Administration (Research Protocols)

Mechanism of Action – Selanka Research

Modulation of the GABAergic System

Research suggests that Selank modulates the activity of the GABAergic system—but without directly binding to the GABA-A receptor, which distinguishes its mechanism of action from that of classical benzodiazepines. Preclinical studies have observed anxiolytic effects without the characteristic sedation and muscle relaxation typical of benzodiazepines (Semenova et al., Bulletin of Experimental Biology and Medicine, 2010). This profile makes Selank a subject of research in the field of so-called “pure anxiolysis.”

Enkephalinase Inhibition and the Opioid System

One of the research hypotheses suggests that Selank may act as an inhibitor of enkephalinase—an enzyme that cleaves the endogenous opioid peptides Met-enkephalin and Leu-enkephalin. Preclinical studies have reported increased levels of Met-enkephalin in the brain following administration of Selank (Semenova et al., 2009). The enkephalin system is the subject of research in connection with the regulation of emotions and the stress response.

Selanka’s Areas of Scientific Research

Research on anxiolytic properties

Preclinical studies in animal models (particularly mice and rats) suggest that Selank has anxiolytic properties in tests such as the elevated plus maze and the open field test. A key research finding is the potential absence of a sedative, amnesic, or addictive profile, which is typical of benzodiazepines. These results apply exclusively to animal models.

Research on Memory and Cognitive Functions

Research using animal models has observed improvements in short-term memory under stressful conditions following administration of Selank (Uchakina et al., 2014). The mechanism is associated with the modulation of BDNF and dopaminergic neurotransmission in the hippocampus. In this area, there is a research parallel with Semax, making these two peptides the subject of comparative studies.

Research on the Immune System (Tuftsin-Based)

Because Selank is derived from Tuftsin—a tetrapeptide that occurs naturally through the cleavage of IgG and acts as an immunomodulator—research has also focused on its potential effects on the immune system. Preclinical studies examined its effects on the activity of natural killer (NK) cells and macrophage phagocytosis. These results were obtained under laboratory conditions.

Comparison of Selank and Semax

Feature	Selank	Semax
Sequence	Thr-Lys-Pro-Arg-Pro-Gly-Pro	Met-Glu-His-Phe-Pro-Gly-Pro
Basic Information	Tuftsin Analog (immunomodulator)	ACTH(4-7) analog
Primary Research Interest	Anxiolysis, GABA modulation	BDNF expression, cognition
Immunology Research	Yes (Tuftsin foundation)	Minimal
Russian registration	Yes (anxiolytic)	Yes (neurology)
Contents (jacked.sk)	10 mg	20 mg

Technical Specifications

Parameter	Value
Contents	10 mg freeze-dried powder
Purity	≥98% (HPLC)
Molecular weight	863.0 Da
Appearance	White freeze-dried powder
Storage	−20 °C (long-term), 4 °C (short-term, up to 4 weeks)
Sterility	This product is not sterile—it is not intended for injection or human use
Intended Use	For scientific research purposes only

Frequently Asked Questions About Selanka (FAQ)

What is Selank, and where does the name come from?

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed in Russia as a stabilized analog of the endogenous immunomodulator Tuftsin. Thr-Lys-Pro-Arg is the core sequence derived from Tuftsin, to which the Pro-Gly-Pro extension was added to increase metabolic stability. It is available on jacked.sk exclusively for scientific research purposes.

How does Selank differ from benzodiazepines in a research context?

Preclinical studies suggest that Selank modulates the GABAergic system without directly binding to the GABA-A receptor—unlike benzodiazepines. Research has observed an anxiolytic profile without the typical sedation, muscle relaxation, or amnesia that are characteristic of benzodiazepines in animal models. These results do not apply to human use.

Is Selank registered as a drug in the European Union?

No. Selank is registered as an anxiolytic exclusively in the Russian Federation. It does not have the status of a drug in the European Union, the United States, or any other countries. The products on jacked.sk are intended exclusively for scientific research purposes.

What is the relationship between Selanko and Tuftsin?

Tuftsin is an endogenous tetrapeptide (Thr-Lys-Pro-Arg) formed by the enzymatic cleavage of the IgG heavy chain in the spleen. It acts as a natural immunomodulator that stimulates phagocytosis. Selank was synthesized by adding Pro-Gly-Pro to the C-terminal end of Tuftsin, which increases the biological stability of the parent sequence.

How should Selank 10 mg be stored to maintain its quality?

It is recommended to store Selank 10 mg lyophilized powder at −20 °C, protected from light and moisture. For short-term use (up to 4 weeks), a temperature of 4 °C is sufficient. Stability is reduced after reconstitution—we recommend referring to the reconstitution protocol in the Dosage Calculator section on jacked.sk.

What is the purity of Selanka on jacked.sk?

Selank 10 mg has a purity of ≥98%, verified by HPLC (high-performance liquid chromatography). The Certificate of Analysis (COA) is available upon request in the /certificates-of-analysis/ section. HPLC analysis confirms the identity, purity, and absence of undesirable impurities.

⚠️ Warning – Intended exclusively for research purposes

All products sold on jacked.sk are intended EXCLUSIVELY for scientific research purposes. They are not intended for use as a medicine, drug, dietary supplement, or cosmetic product, nor for human or veterinary use. The results cited in the descriptions are based on preclinical studies (in vitro, animal models) and cannot be automatically extrapolated to human use. Sale restricted to individuals over the age of 18. By purchasing this product, the customer confirms that they are a professional researcher and will use the product solely in accordance with applicable laws.