{"id":785,"date":"2017-05-12T08:58:01","date_gmt":"2017-05-12T06:58:01","guid":{"rendered":"https:\/\/jacked.sk\/obchod\/aod-9604\/"},"modified":"2026-08-21T14:40:56","modified_gmt":"2026-08-21T12:40:56","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/dev.jacked.sk\/en\/research-on-muscle-growth\/aod-9604\/","title":{"rendered":"AOD-9604 5 mg"},"content":{"rendered":"<div class=\"row read-more\"  id=\"row-905554675\">\n\n\t<div id=\"col-536254386\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h1>AOD-9604 5 mg \u2013 Lipolytic HGH Fragment for Metabolic Research<\/h1>\n<p>\u26a0\ufe0f <strong>Warning:<\/strong> This product is intended <strong>solely for scientific research purposes<\/strong> (<em>research use only<\/em>). It is not intended for use as a medicine, drug, dietary supplement, or for human use. Sale restricted to individuals over the age of 18.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-286067208\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 (Anti-Obesity Drug 9604) is a synthetic peptide derived from the C-terminal fragment of human growth hormone (HGH)\u2014specifically residues 176\u2013191. Unlike native HGH, the N-terminal group is modified by the substitution of phenylalanine for tyrosine (Tyr\u2192Phe), which fundamentally alters its pharmacological profile. <\/p>\n<p>The peptide was originally developed by the Australian company <strong>Metabolic Pharmaceuticals Ltd.<\/strong> with the aim of isolating the lipolytic properties of HGH without its undesirable metabolic effects\u2014specifically, without the diabetogenic and growth effects associated with the whole growth hormone molecule.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1861176518\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Origin and Development: Metabolic Pharmaceuticals Ltd.<\/h3>\n<p>Metabolic Pharmaceuticals Ltd. (Australia) has initiated a series of preclinical and clinical studies focused on research into adipose tissue metabolism. AOD-9604 has undergone Phase 2A clinical trials for obesity, making it one of the well-documented investigational compounds in its class.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-621417059\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Mechanism of Action in Research<\/h2>\n<h3>Relationship to Growth Hormone (HGH)<\/h3>\n<p>Native HGH exhibits two distinct groups of biological activities: (1) growth and diabetogenic effects mediated by the N-terminal region of the molecule, and (2) lipolytic effects localized in the C-terminal fragment (residues 176\u2013191). AOD-9604 is an isolated C-terminal fragment designed to preserve lipolytic activity without the growth-promoting and insulin-resistance-inducing effects of full-length HGH. <\/p>\n<h3>Beta-3 adrenergic receptors and lipolysis in adipose tissue<\/h3>\n<p>Preclinical studies suggest that AOD-9604 acts on <strong>beta-3 adrenergic receptors<\/strong> in adipose tissue. In in vitro and in vivo models (animal studies), the following was observed: <\/p>\n<ul>\n<li><strong>Stimulation of lipolysis<\/strong> \u2013 mobilization of stored fat in adipocytes<\/li>\n<li><strong>Inhibition of lipogenesis<\/strong> \u2013 suppression of the formation of new fat stores<\/li>\n<\/ul>\n<p>These mechanisms have been studied primarily in animal models (mouse and rat models of obesity). The results from preclinical studies serve as the basis for further scientific research.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-689899099\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Clinical Research Status<\/h2>\n<h3>FDA GRAS status and Phase 2A clinical trials (obesity)<\/h3>\n<p>AOD-9604 has been granted <strong>GRAS (Generally Recognized As Safe)<\/strong> status by the U.S. FDA for food use, which confirms its safety profile based on available scientific data.<\/p>\n<p>As part of Metabolic Pharmaceuticals Ltd.\u2019s clinical program, <strong>Phase 2A<\/strong> studies were conducted to investigate weight management in obese patients. The results of these studies are publicly available and form the basis for further research into lipolytic peptides. <\/p>\n<p><strong>Clinical status:<\/strong> AOD-9604 is not approved as a registered drug in the EU or in Slovakia. It is the subject of scientific research.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1895333589\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Technical Specifications and Storage<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Parameter<\/strong><\/td>\n<td><strong>Value<\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong>Form<\/strong><\/td>\n<td>Freeze-dried powder<\/td>\n<\/tr>\n<tr>\n<td><strong>Quantity<\/strong><\/td>\n<td>5 mg per bottle<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity<\/strong><\/td>\n<td>\u226598% (HPLC verified)<\/td>\n<\/tr>\n<tr>\n<td><strong>CAS Number<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular weight<\/strong><\/td>\n<td>1,817.9 Da<\/td>\n<\/tr>\n<tr>\n<td><strong>Sequence<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage (long-term)<\/strong><\/td>\n<td>-20 \u00b0C (lyophilized)<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage (after reconstruction)<\/strong><\/td>\n<td>2\u20138 \u00b0C, use within 28 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Reconstitution<\/strong><\/td>\n<td>Bacteriostatic water or sterile water<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-263702912\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Frequently Asked Questions About AOD-9604 (FAQ)<\/h2>\n<div class=\"accordion\">\n\t<div id=\"accordion-3251758497\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3251758497-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-aod-9604,-and-what-is-the-scientific-research-on-this-peptide?\" aria-expanded=\"false\" aria-controls=\"accordion-3251758497-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is AOD-9604, and what is the scientific research on this peptide?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3251758497-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3251758497-label\">\n\t\t\t\n<p>AOD-9604 is a synthetic fragment of human growth hormone (residues 176\u2013191). Scientific research focuses on its lipolytic properties\u2014its ability to stimulate the breakdown of adipose tissue in in vitro and in vivo models without the effects of full-length HGH.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-296361822\" class=\"accordion-item\">\n\t\t<a id=\"accordion-296361822-label\" class=\"accordion-title plain\" href=\"#accordion-item-why-does-aod-9604-have-fda-gras-status?\" aria-expanded=\"false\" aria-controls=\"accordion-296361822-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Why does AOD-9604 have FDA GRAS status?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-296361822-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-296361822-label\">\n\t\t\t\n<p>FDA GRAS (<em>Generally Recognized As Safe<\/em>) is a status granted to substances considered safe based on available scientific data. This status has been granted to AOD-9604 for food use and demonstrates the safety profile of this compound.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-3311024981\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3311024981-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-the-difference-between-aod-9604-and-full-length-hgh?\" aria-expanded=\"false\" aria-controls=\"accordion-3311024981-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is the difference between AOD-9604 and full-length HGH?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3311024981-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3311024981-label\">\n\t\t\t\n<p>Full-length growth hormone (HGH) has a wide range of metabolic effects, including growth-promoting and diabetogenic effects. AOD-9604 is an isolated C-terminal fragment that, according to preclinical studies, retains lipolytic properties without these undesirable effects.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-4176963573\" class=\"accordion-item\">\n\t\t<a id=\"accordion-4176963573-label\" class=\"accordion-title plain\" href=\"#accordion-item-how-is-aod-9604-reconstituted-for-research-use?\" aria-expanded=\"false\" aria-controls=\"accordion-4176963573-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>How is AOD-9604 reconstituted for research use?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-4176963573-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-4176963573-label\">\n\t\t\t\n<p>The lyophilized powder should be reconstituted with bacteriostatic or sterile water. For exact volumes, use the dosing calculator at jacked.sk. Store the reconstituted solution at 2\u20138 \u00b0C and use within 28 days.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-1980412061\" class=\"accordion-item\">\n\t\t<a id=\"accordion-1980412061-label\" class=\"accordion-title plain\" href=\"#accordion-item-how-pure-is-the-aod-9604-from-jacked.sk?\" aria-expanded=\"false\" aria-controls=\"accordion-1980412061-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>How pure is the AOD-9604 from jacked.sk?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-1980412061-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-1980412061-label\">\n\t\t\t\n<p>Each batch of AOD-9604 has a purity of \u226598%, as verified by HPLC (high-performance liquid chromatography). A Certificate of Analysis (COA) is available upon request.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-1477043199\" class=\"accordion-item\">\n\t\t<a id=\"accordion-1477043199-label\" class=\"accordion-title plain\" href=\"#accordion-item-is-aod-9604-legal-for-research-purposes-in-slovakia?\" aria-expanded=\"false\" aria-controls=\"accordion-1477043199-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Is AOD-9604 legal for research purposes in Slovakia?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-1477043199-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-1477043199-label\">\n\t\t\t\n<p>AOD-9604, sold on jacked.sk, is intended exclusively for scientific research purposes. It is not classified as a controlled substance in Slovakia. The customer is responsible for complying with applicable laws in their jurisdiction.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-729926319\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t<div class=\"is-border\"\n\t\tstyle=\"border-color:#fe5000;border-width:1px 1px 1px 1px;\">\n\t<\/div>\n\t\t\t\n<h4>\u26a0\ufe0f Warning \u2013 Intended exclusively for research purposes<\/h4>\n<p><strong>All products sold on jacked.sk are intended EXCLUSIVELY for scientific research purposes.<\/strong>  They are not intended for use as a medicine, drug, dietary supplement, or cosmetic product, nor for human or veterinary use. The results cited in the descriptions are based on preclinical studies (in vitro, animal models) and cannot be automatically extrapolated to human use. Sale restricted to individuals over the age of 18. By purchasing this product, the customer confirms that they are a professional researcher and will use the product solely in accordance with applicable laws.<\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-729926319 > .col-inner {\n  padding: 0.5rem 0.5rem 0.5rem 0.5rem;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic C-terminal fragment of growth hormone (residues 176\u2013191), designed to isolate the lipolytic properties of HGH <strong>without its growth-promoting and diabetogenic effects<\/strong>. It has undergone Phase 2A clinical trials and has FDA GRAS status\u2014making it one of the best-documented compounds in its class. <\/p>\n<ul>\n<li>Purity <strong>\u2265 98%<\/strong> \u2013 Each batch verified by HPLC; COA available upon request<\/li>\n<li>5 mg of lyophilized powder, \u221220 \u00b0C | after reconstitution, store at 2\u20138 \u00b0C for up to 28 days<\/li>\n<li>Shipped within 48 hours<\/li>\n<\/ul>\n","protected":false},"featured_media":2995,"template":"","meta":[],"product_brand":[],"product_cat":[141,153],"product_tag":[161,162],"class_list":["post-785","product","type-product","status-publish","has-post-thumbnail","product_cat-research-on-muscle-growth","product_cat-research-on-weight-loss-and-metabolism","product_tag-aod-9604","product_tag-fat-burning","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product\/785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/media\/2995"}],"wp:attachment":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/media?parent=785"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_brand?post=785"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_cat?post=785"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_tag?post=785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}