{"id":3380,"date":"2023-07-13T22:41:30","date_gmt":"2023-07-13T20:41:30","guid":{"rendered":"https:\/\/jacked.sk\/obchod\/thymosin-alpha-1-immune-support\/"},"modified":"2026-08-21T14:22:14","modified_gmt":"2026-08-21T12:22:14","slug":"thymosin-alpha-1-immune-support","status":"publish","type":"product","link":"https:\/\/dev.jacked.sk\/en\/research-on-tissue-regeneration-and-healing\/thymosin-alpha-1-immune-support\/","title":{"rendered":"Thymosin Alpha 1 10 mg"},"content":{"rendered":"
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Thymosin Alpha-1 10 mg \u2013 Immunomodulatory Peptide for Immunity Research<\/h1>\n

\u26a0\ufe0f Legal Notice:<\/strong> Thymosin Alpha-1 is intended exclusively for scientific and research purposes. It is not intended for human use as a medication, dietary supplement, or cosmetic product. Sale restricted to individuals over the age of 18.
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What is Thymosin Alpha-1?<\/h2>\n

Thymosin Alpha-1 (abbreviated as T\u03b11 or TA1) is a 28-amino acid polypeptide<\/strong> that is naturally produced and secreted by the thymus gland. It is a biologically active fragment of a larger precursor protein\u2014prothymosin alpha. The natural sequence of the peptide begins with an acetylated serine-alanine-alanine-valine core:
\nAc-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
\nThymosin Alpha-1 has been one of the most thoroughly studied immunomodulatory peptides<\/strong> since the 1970s. Research into its biological activity was initiated in the United States, where Dr. Allan Goldstein\u2019s team identified and isolated the first thymosin fractions. Today, T\u03b11 is the subject of international scientific interest, particularly in the fields of immunology, oncology, and infectious diseases.
\nImportant: Thymosin Alpha-1 is not approved as a drug<\/strong> for general use in the European Union<\/strong>. All available preclinical and clinical data serve as a basis for further scientific research and are accessible in PubMed databases.
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Mechanism of Action \u2013 How T\u03b11 Works in Research<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Modulation of T-cell Differentiation and Proliferation<\/h3>\n

Research has identified Thymosin Alpha-1 as a regulator of T-lymphocyte differentiation and maturation<\/strong> in the thymus. In preclinical studies, T\u03b11 has been shown to influence the conversion of immature thymocytes into functional T cells (CD4+ and CD8+). This mechanism is the subject of research in the context of conditions associated with thymus dysfunction or immunosuppression.
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Activation of dendritic cells<\/h3>\n

Dendritic cells are key antigen-presenting cells of the immune system\u2014they bridge innate and adaptive immunity. Research has shown that T\u03b11 can stimulate the maturation and activation of dendritic cells<\/strong>, thereby potentially enhancing antigen presentation to T lymphocytes. This mechanism is being studied in the field of adjuvants in immunological research.
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Regulation of pro-inflammatory cytokines<\/h3>\n

Preclinical studies document the modulatory effect of T\u03b11 on the production of key cytokines involved in the immune response, including IL-2 (interleukin-2)<\/strong> and IFN-\u03b3 (interferon-gamma)<\/strong>. Both cytokines play a central role in cellular immunity and antiviral defense. Research is investigating how T\u03b11 regulates the balance between inflammatory and anti-inflammatory responses.
\nSources: Goldstein AL. et al., Thymosin alpha 1 \u2013 Annals of the New York Academy of Sciences (2007); Tuthill C. et al., Expert Opinion on Biological Therapy (2006) <\/em>
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Research Areas: Thymosin Alpha-1<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Immunodeficiency and Tumor Immunology<\/h3>\n

Thymosin Alpha-1 has been studied as a potential immunorestorative agent in conditions characterized by impaired T-cell function. In the field of tumor immunology, T\u03b11 has been tested as an adjuvant<\/strong> in combination with other modalities\u2014the hypothesis being that restoring immune competence may enhance the body\u2019s antitumor mechanisms.
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Sepsis \u2013 Preclinical Models<\/h3>\n

Several preclinical studies have investigated T\u03b11 in sepsis models (CLP models in rodents). The results suggest a potential for modulating the immune response in the context of systemic inflammatory syndrome. However, these data come exclusively from animal models, and their translation into clinical practice requires further research.
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Research in the Context of Viral Infections (2020\u20132022)<\/h3>\n

Between 2020 and 2022, several observational studies and pilot clinical trials were published that focused on the potential immunomodulatory role of T\u03b11 in severe viral infections. These studies primarily examined the modulation of the inflammatory response and the restoration of T-cell function. The results are preliminary and do not imply any clinical recommendations.
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Clinical and Regulatory Context: Zadaxin\u00ae<\/h2>\n

Thymosin Alpha-1 was commercially developed under the name Zadaxin\u00ae (thymalfasin)<\/strong> by SciClone Pharmaceuticals. Zadaxin\u00ae is approved in more than 35 countries<\/strong> (primarily in Asia, Latin America, and the Middle East) as a treatment for chronic hepatitis B, hepatitis C, and as an adjuvant therapy for certain cancers.
\nImportant Notice: Zadaxin\u00ae is not approved by the European Medicines Agency (EMA) or the U.S. FDA<\/strong> for these indications. Thymosin Alpha-1 sold on jacked.sk is not the same as Zadaxin\u00ae\u2014it is a research compound intended exclusively for laboratory and scientific purposes, not for human use.
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Technical Specifications<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n
Parameter<\/strong><\/td>\nValue<\/strong><\/td>\n<\/tr>\n
Chemical Name<\/strong><\/td>\nThymosin Alpha-1 (Thymalfasin, T\u03b11)<\/td>\n<\/tr>\n
Sequence length<\/strong><\/td>\n28 amino acids<\/td>\n<\/tr>\n
Molecular weight<\/strong><\/td>\n3,108.3 Da<\/td>\n<\/tr>\n
CAS Number<\/strong><\/td>\n62304-98-7<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nLyophilized (freeze-dried) white powder<\/td>\n<\/tr>\n
Contents per package<\/strong><\/td>\n10 mg<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u2265 98% (HPLC-verified)<\/td>\n<\/tr>\n
Recommended storage conditions<\/strong><\/td>\n\u221220 \u00b0C, protected from light and moisture<\/td>\n<\/tr>\n
Intended Use<\/strong><\/td>\nFor scientific research purposes only<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Frequently Asked Questions About Thymosin Alpha-1<\/h2>\n
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