{"id":3120,"date":"2023-02-19T12:20:39","date_gmt":"2023-02-19T11:20:39","guid":{"rendered":"https:\/\/jacked.sk\/obchod\/mix-tb-500-bpc-157\/"},"modified":"2026-08-21T14:31:17","modified_gmt":"2026-08-21T12:31:17","slug":"mix-tb-500-bpc-157-10mg","status":"publish","type":"product","link":"https:\/\/dev.jacked.sk\/en\/research-on-tissue-regeneration-and-healing\/mix-tb-500-bpc-157-10mg\/","title":{"rendered":"TB 500 &#038; BPC 157 10 mg Mix"},"content":{"rendered":"<div class=\"row read-more\"  id=\"row-892548176\">\n\n\t<div id=\"col-1400043983\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h1>TB-500 &#038; BPC-157 10 mg Mix \u2013 Pre-mixed Stack for Regeneration Research<\/h1>\n<p>\u26a0\ufe0f <strong>Warning:<\/strong> This product is intended <strong>solely for scientific research purposes<\/strong> (<em>research use only<\/em>). It is not intended for use as a medicine, drug, dietary supplement, or for human use. Sale restricted to individuals over the age of 18.<br \/>\n<strong>The TB-500 &#038; BPC-157 Mix<\/strong> is a premixed research compound containing <strong>5 mg of BPC-157<\/strong> and <strong>5 mg of TB-500<\/strong> in a single lyophilized vial (total weight 10 mg). This stack was designed for researchers investigating the synergistic effects of both peptides and seeking simpler sample preparation for laboratory work. Both peptides are individually the subject of extensive preclinical research; the combination is the subject of studies on complementary regenerative mechanisms. On jacked.sk, the TB-500 &#038; BPC-157 Mix is available exclusively for scientific research purposes.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-151555455\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>What is the TB-500 &#038; BPC-157 Mix?<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1254413862\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Ingredients: 5 mg BPC-157 + 5 mg TB-500 in one vial<\/h3>\n<p>The mix contains precisely measured amounts of two different research peptides:<\/p>\n<ul>\n<li><strong>BPC-157 (Body Protection Compound 157)<\/strong> \u2013 a synthetic pentadecapeptide (15 amino acids) isolated from human gastric juice; purity of each component \u226598%<\/li>\n<li><strong>TB-500 (Thymosin Beta-4)<\/strong> \u2013 a synthetic version of a 43-amino acid endogenous peptide; purity of each component \u226598%<\/li>\n<\/ul>\n<p>Each ingredient is individually tested using HPLC before premixing, which ensures the accuracy of the declared composition.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1465388450\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Why a premixed stack? Benefits for research <\/h3>\n<p>For researchers who routinely work with both peptides, the premixed stack offers several practical advantages: a reduction in the number of reconstitutions, precise 1:1 ratio dosing, fewer vials, and logistical simplicity in preparing laboratory protocols. Researchers who need variable component ratios may prefer to purchase individual peptides separately.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-11070066\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>The Scientific Basis of the Combination: Complementary Mechanisms<\/h2>\n<p>Scientific interest in the combination of BPC-157 and TB-500 is based on the assumption that both peptides act through distinct but potentially synergistic mechanisms at different levels of the biological response to injury.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1813975857\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>BPC-157 \u2013 Local Regeneration Axis (FAK-paxillin \/ NO Synthase)<\/h3>\n<p>BPC-157 acts primarily through <strong>the FAK-paxillin<\/strong> (focal adhesion kinase) and <strong>NO synthase<\/strong> (nitric oxide synthase) <strong>signaling pathway<\/strong>. Research in animal models has observed its effect on wound and tissue healing in the immediate vicinity of the lesion\u2014therefore, the effects of BPC-157 are described in the literature as <strong>local and targeted<\/strong>. BPC-157 is a fragment of the BPC protein isolated from human gastric juice and has demonstrated stability in the acidic environment of the stomach in preclinical models.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-535958767\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>TB-500 \u2013 Systemic Regeneration Axis (Actin Mechanism)<\/h3>\n<p>TB-500 acts by <strong>binding to G-actin<\/strong> via the LKKTETQ sequence, thereby regulating the polymerization of actin filaments. This mechanism has <strong>a<\/strong> much broader, <strong>systemic nature<\/strong> \u2014it influences cell migration, angiogenesis, and the tissue response to injury throughout the body. Thymosin Beta-4 is naturally present in platelets, suggesting a role in the systemic coordination of repair processes.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-336923223\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Preclinical Research on Combined Administration<\/h3>\n<p>In studies using rat models, <strong>the combined administration of BPC-157 and TB-500<\/strong> was investigated in various types of tissue injuries. Preclinical data suggest that the local effect of BPC-157 and the systemic effect of TB-500 are complementary\u2014a hypothesis that underpins the research interest in this combination. These results are preclinical and do not indicate effects in humans.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1371013648\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Overview of Research Areas for the Combination of BPC-157 and TB-500<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1691073081\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Tendons and Ligaments<\/h3>\n<p>Preclinical research using animal models examined the effect of a combination of BPC-157 and TB-500 on tendon (Achilles tendon) and ligament (anterior cruciate ligaments) injuries. The research observed accelerated histological healing and improved mechanical properties of the regenerated tissues compared to the control groups.   <em>(Hsieh MJ et al., studies in rat models)<\/em><br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-287679164\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>Gastrointestinal tract<\/h3>\n<p>BPC-157 has been particularly well studied in preclinical models in the context of the GI tract\u2014its gastroprotective and ulcer-protective properties are among the most extensively documented areas of research on this peptide. TB-500 complements this mechanism by influencing angiogenesis in the GI tract mucosa. Combined research using models of inflammatory bowel disease (IBD) is an active area of study.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1464194741\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h3>The Heart Muscle and the Circulatory System<\/h3>\n<p>Both peptides have a documented effect on the cardiovascular system in preclinical models: TB-500 through the migration of cardiomyocyte progenitors and the reduction of apoptosis following ischemic injury, and BPC-157 through NO-dependent angiogenesis and vascular protection. The combined study is investigating whether these effects are additive or synergistic.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-670373185\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Mixtures vs. Individual Compounds \u2013 When to Use Which in Research<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Situation<\/strong><\/td>\n<td><strong>Recommendations for Research<\/strong><\/td>\n<\/tr>\n<tr>\n<td>Research on the synergistic effect of both peptides in a 1:1 ratio<\/td>\n<td>TB-500 &#038; BPC-157 Mix 10 mg<\/td>\n<\/tr>\n<tr>\n<td>Research requiring a variable ratio of BPC-157 to TB-500<\/td>\n<td>Individual products (BPC-157 5 mg + TB-500 5 mg)<\/td>\n<\/tr>\n<tr>\n<td>Research on the Mechanism of Action of BPC-157 Alone<\/td>\n<td>BPC-157 5 mg alone<\/td>\n<\/tr>\n<tr>\n<td>Research on the Mechanism of Action of TB-500 Alone<\/td>\n<td>TB-500 5 mg alone<\/td>\n<\/tr>\n<tr>\n<td>Pilot study using a standard 1:1 protocol<\/td>\n<td>Mix \u2013 Simpler Logistics<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-608159846\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Product Technical Specifications<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Parameter<\/strong><\/td>\n<td><strong>Value<\/strong><\/td>\n<\/tr>\n<tr>\n<td>Ingredients<\/td>\n<td>5 mg BPC-157 + 5 mg TB-500<\/td>\n<\/tr>\n<tr>\n<td>Total weight<\/td>\n<td>10 mg<\/td>\n<\/tr>\n<tr>\n<td>Form<\/td>\n<td>Freeze-dried powder (lyophilisate)<\/td>\n<\/tr>\n<tr>\n<td>Purity of each component<\/td>\n<td>\u226598% (HPLC-verified)<\/td>\n<\/tr>\n<tr>\n<td>Storage<\/td>\n<td>\u221220 \u00b0C (long-term); 2\u20138 \u00b0C (after reconstitution, up to 30 days)<\/td>\n<\/tr>\n<tr>\n<td>Intended Use<\/td>\n<td>For scientific research purposes only<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-978454605\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Storage and Reconstitution for Research Use<\/h2>\n<p>The lyophilized mixture is stable at <strong>\u221220 \u00b0C<\/strong> in its original, sealed packaging. For reconstitution in laboratory research, <strong>bacteriostatic water for injection<\/strong> or sterile water is used\u2014the same principles apply to the premixed product as to the individual peptides. After reconstitution, the product is stable at 2\u20138 \u00b0C for 30 days. Repeated freezing reduces the integrity of both peptide components\u2014therefore, aliquoting is recommended before the first freezing.<br \/>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-2121375673\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2>Frequently Asked Questions About the TB-500 &#038; BPC-157 Mix (FAQ)<\/h2>\n<div class=\"accordion\">\n\t<div id=\"accordion-323142058\" class=\"accordion-item\">\n\t\t<a id=\"accordion-323142058-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-in-the-tb-500-&#038;-bpc-157-mix?\" aria-expanded=\"false\" aria-controls=\"accordion-323142058-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is in the TB-500 &amp; BPC-157 Mix?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-323142058-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-323142058-label\">\n\t\t\t\nThe TB-500 &#038; BPC-157 blend contains <strong>5 mg of BPC-157<\/strong> (Body Protection Compound 157, a 15-amino acid peptide) and <strong>5 mg of TB-500<\/strong> (synthetic Thymosin Beta-4, 43 amino acids) in a single lyophilized vial with a total weight of 10 mg. The purity of each component is \u226598%, as verified by HPLC analysis. This product is intended exclusively for scientific research purposes.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-596449138\" class=\"accordion-item\">\n\t\t<a id=\"accordion-596449138-label\" class=\"accordion-title plain\" href=\"#accordion-item-why-do-researchers-combine-tb-500-with-bpc-157?\" aria-expanded=\"false\" aria-controls=\"accordion-596449138-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Why do researchers combine TB-500 with BPC-157?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-596449138-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-596449138-label\">\n\t\t\t\nScientific interest in this combination stems from the complementary nature of the mechanisms: <strong>BPC-157<\/strong> acts locally via the FAK-paxillin signaling pathway and NO synthase, while <strong>TB-500<\/strong> acts systemically via the actin mechanism. Preclinical research in animal models suggests that these mechanisms complement each other in various types of tissue injuries\u2014tendons, ligaments, the GI tract, and the heart muscle. The combination is the subject of active preclinical research.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-1701205248\" class=\"accordion-item\">\n\t\t<a id=\"accordion-1701205248-label\" class=\"accordion-title plain\" href=\"#accordion-item-does-it-make-sense-to-buy-a-blend-instead-of-individual-peptides?\" aria-expanded=\"false\" aria-controls=\"accordion-1701205248-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Does it make sense to buy a blend instead of individual peptides?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-1701205248-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-1701205248-label\">\n\t\t\t\nFor researchers working with <strong>a fixed 1:1 protocol<\/strong> (equal amounts of both peptides), the premixed product is more convenient\u2014it reduces the number of reconstitutions, simplifies logistics, and ensures precise proportional dosing. For research requiring <strong>a variable ratio<\/strong> of components (such as 2:1 or 1:2), it is more suitable to purchase the individual peptides separately.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-2286680703\" class=\"accordion-item\">\n\t\t<a id=\"accordion-2286680703-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-the-purity-of-each-ingredient-in-the-mix?\" aria-expanded=\"false\" aria-controls=\"accordion-2286680703-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is the purity of each ingredient in the mix?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-2286680703-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-2286680703-label\">\n\t\t\t\nThe purity of each component (both BPC-157 and TB-500) is <strong>\u226598%<\/strong>, as verified by HPLC (high-performance liquid chromatography) prior to premixing. A Certificate of Analysis (CoA) is available for each batch. The CoA includes the molecular identification, percentage purity, and analytical method results.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-2893102982\" class=\"accordion-item\">\n\t\t<a id=\"accordion-2893102982-label\" class=\"accordion-title plain\" href=\"#accordion-item-how-should-mix-tb-500-&#038;-bpc-157-be-stored-and-reconstituted?\" aria-expanded=\"false\" aria-controls=\"accordion-2893102982-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>How should Mix TB-500 &amp; BPC-157 be stored and reconstituted?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-2893102982-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-2893102982-label\">\n\t\t\t\nStore the lyophilized mixture at <strong>\u221220 \u00b0C<\/strong> in its original, sealed container (stable for 24 months). Use <strong>bacteriostatic water for injection<\/strong> for reconstitution (the standard volume depends on the desired experimental concentration). After reconstitution, store at 2\u20138 \u00b0C and use within 30 days. Protect the product from light and repeated freezing.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-3678402471\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3678402471-label\" class=\"accordion-title plain\" href=\"#accordion-item-is-it-better-to-use-a-mix-or-individual-peptides-in-research?\" aria-expanded=\"false\" aria-controls=\"accordion-3678402471-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Is it better to use a mix or individual peptides in research?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3678402471-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3678402471-label\">\n\t\t\t\nIt depends on the research protocol. <strong>The mix<\/strong> is more practical when using a fixed 1:1 ratio and a standard research protocol. <strong>Individual peptides<\/strong> are more suitable when the research requires different dosages of each component, when you want to monitor the effect of each peptide in isolation, or when you need a larger amount of one of the components. Both approaches are valid in scientific research.<br \/>\n\t\t<\/div>\n\t<\/div>\n\t\n<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-727737600\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t<div class=\"is-border\"\n\t\tstyle=\"border-color:#fe5000;border-width:1px 1px 1px 1px;\">\n\t<\/div>\n\t\t\t\n<h4>\u26a0\ufe0f Warning \u2013 Intended exclusively for research purposes<\/h4>\n<p><strong>All products sold on jacked.sk are intended EXCLUSIVELY for scientific research purposes.<\/strong>  They are not intended for use as a medicine, drug, dietary supplement, or cosmetic product, nor for human or veterinary use. The results cited in the descriptions are based on preclinical studies (in vitro, animal models) and cannot be automatically extrapolated to human use. Sale restricted to individuals over the age of 18. By purchasing this product, the customer confirms that they are a professional researcher and will use the product solely in accordance with applicable laws.<br \/>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-727737600 > .col-inner {\n  padding: 0.5rem 0.5rem 0.5rem 0.5rem;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A premixed stack of <strong>5 mg BPC-157 + 5 mg TB-500<\/strong> in a single vial. BPC-157 acts locally via the FAK-paxillin pathway, while TB-500 acts systemically by binding to actin\u2014this combination is currently being studied for its complementary regenerative mechanisms. Fewer reconstitutions, an exact 1:1 ratio, and fewer vials in the protocol.  <\/p>\n<ul>\n<li>Purity of each component <strong>\u2265 98%<\/strong> \u2013 HPLC prior to premixing, COA available upon request<\/li>\n<li>10 mg of lyophilized powder (5 + 5 mg), \u221220 \u00b0C | 2\u20138 \u00b0C for up to 30 days after reconstitution<\/li>\n<li>Shipped within 48 hours<\/li>\n<\/ul>\n","protected":false},"featured_media":3023,"template":"","meta":[],"product_brand":[],"product_cat":[137],"product_tag":[177],"class_list":["post-3120","product","type-product","status-publish","has-post-thumbnail","product_cat-research-on-tissue-regeneration-and-healing","product_tag-mix-of-tb-500-bpc-157","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product\/3120","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/media\/3023"}],"wp:attachment":[{"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/media?parent=3120"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_brand?post=3120"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_cat?post=3120"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/dev.jacked.sk\/en\/wp-json\/wp\/v2\/product_tag?post=3120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}