{"id":3119,"date":"2023-02-19T12:33:57","date_gmt":"2023-02-19T11:33:57","guid":{"rendered":"https:\/\/jacked.sk\/obchod\/selank-10mg\/"},"modified":"2026-08-21T14:30:34","modified_gmt":"2026-08-21T12:30:34","slug":"selank-10mg","status":"publish","type":"product","link":"https:\/\/dev.jacked.sk\/en\/research-on-cognitive-functions\/selank-10mg\/","title":{"rendered":"Selank 10 mg"},"content":{"rendered":"
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H1: Selank 10 mg \u2013 Anxiolytic Heptapeptide for Neuroscience Research<\/h1>\n

\u26a0\ufe0f Warning:<\/strong> Selank sold on jacked.sk is intended exclusively for scientific research purposes<\/strong> (research use only<\/em>). It is not intended for human use; it is not a drug, dietary supplement, or cosmetic product. Intended only for qualified researchers.
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What is Selank? Origin and Scientific Basis <\/h2>\n

Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro<\/strong>. It was designed as a stabilized analog of the endogenous immunomodulator Tuftsin<\/strong> (Thr-Lys-Pro-Arg), to which a Pro-Gly-Pro extension was added\u2014the same approach used in the development of Semax. This extension increases the peptide\u2019s metabolic resistance to enzymatic degradation.
\nSelank was developed in collaboration between the Institute of Molecular Genetics of the RAS<\/strong> (Russian Academy of Sciences) and the Institute of Higher Nervous Activity and Neurophysiology of the RAS<\/strong> in Moscow. It has been registered in the Russian Federation as an anxiolytic\u2014however, this approval does not apply in European Union countries or the United States. In the international research community, Selank is classified as a neuropeptide with an anxiolytic and nootropic profile currently under investigation<\/strong>.
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Chemical Structure and Properties<\/h2>\n\n\n\n\n\n\n\n\n\n\n
Parameter<\/strong><\/td>\nValue<\/strong><\/td>\n<\/tr>\n
Sequence<\/td>\nThr-Lys-Pro-Arg-Pro-Gly-Pro<\/td>\n<\/tr>\n
Class<\/td>\nSynthetic heptapeptide, Tuftsin analog<\/td>\n<\/tr>\n
Molecular weight<\/td>\n863.0 Da<\/td>\n<\/tr>\n
Form (jacked.sk)<\/td>\n10 mg freeze-dried powder<\/td>\n<\/tr>\n
Purity<\/td>\n\u226598% (HPLC-verified)<\/td>\n<\/tr>\n
Storage<\/td>\n\u221220 \u00b0C; protect from light and moisture<\/td>\n<\/tr>\n
Administration in Research<\/td>\nIntranasal Administration (Research Protocols)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Mechanism of Action \u2013 Selanka Research<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Modulation of the GABAergic System<\/h3>\n

Research suggests that Selank modulates the activity of the GABAergic system\u2014but without directly binding to the GABA-A receptor, which distinguishes its mechanism of action from that of classical benzodiazepines. Preclinical studies have observed anxiolytic effects without the characteristic sedation and muscle relaxation typical of benzodiazepines (Semenova et al., Bulletin of Experimental Biology and Medicine<\/em>, 2010). This profile makes Selank a subject of research in the field of so-called \u201cpure anxiolysis.\u201d
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Enkephalinase Inhibition and the Opioid System<\/h3>\n

One of the research hypotheses suggests that Selank may act as an inhibitor of enkephalinase\u2014an enzyme that cleaves the endogenous opioid peptides Met-enkephalin and Leu-enkephalin. Preclinical studies have reported increased levels of Met-enkephalin in the brain following administration of Selank (Semenova et al., 2009). The enkephalin system is the subject of research in connection with the regulation of emotions and the stress response.
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Selanka’s Areas of Scientific Research<\/h2>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Research on anxiolytic properties<\/h3>\n

Preclinical studies in animal models (particularly mice and rats) suggest that Selank has anxiolytic properties in tests such as the elevated plus maze and the open field test. A key research finding is the potential absence of a sedative, amnesic, or addictive profile, which is typical of benzodiazepines. These results apply exclusively to animal models.
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Research on Memory and Cognitive Functions<\/h3>\n

Research using animal models has observed improvements in short-term memory under stressful conditions following administration of Selank (Uchakina et al., 2014). The mechanism is associated with the modulation of BDNF and dopaminergic neurotransmission in the hippocampus. In this area, there is a research parallel with Semax, making these two peptides the subject of comparative studies.
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Research on the Immune System (Tuftsin-Based)<\/h3>\n

Because Selank is derived from Tuftsin\u2014a tetrapeptide that occurs naturally through the cleavage of IgG and acts as an immunomodulator\u2014research has also focused on its potential effects on the immune system. Preclinical studies examined its effects on the activity of natural killer (NK) cells and macrophage phagocytosis. These results were obtained under laboratory conditions.
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Comparison of Selank and Semax<\/h2>\n\n\n\n\n\n\n\n\n\n
Feature<\/strong><\/td>\nSelank<\/strong><\/td>\nSemax<\/strong><\/td>\n<\/tr>\n
Sequence<\/td>\nThr-Lys-Pro-Arg-Pro-Gly-Pro<\/td>\nMet-Glu-His-Phe-Pro-Gly-Pro<\/td>\n<\/tr>\n
Basic Information<\/td>\nTuftsin Analog (immunomodulator)<\/td>\nACTH(4-7) analog<\/td>\n<\/tr>\n
Primary Research Interest<\/td>\nAnxiolysis, GABA modulation<\/td>\nBDNF expression, cognition<\/td>\n<\/tr>\n
Immunology Research<\/td>\nYes (Tuftsin foundation)<\/td>\nMinimal<\/td>\n<\/tr>\n
Russian registration<\/td>\nYes (anxiolytic)<\/td>\nYes (neurology)<\/td>\n<\/tr>\n
Contents (jacked.sk)<\/td>\n10 mg<\/td>\n20 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Technical Specifications<\/h2>\n\n\n\n\n\n\n\n\n\n\n
Parameter<\/strong><\/td>\nValue<\/strong><\/td>\n<\/tr>\n
Contents<\/td>\n10 mg freeze-dried powder<\/td>\n<\/tr>\n
Purity<\/td>\n\u226598% (HPLC)<\/td>\n<\/tr>\n
Molecular weight<\/td>\n863.0 Da<\/td>\n<\/tr>\n
Appearance<\/td>\nWhite freeze-dried powder<\/td>\n<\/tr>\n
Storage<\/td>\n\u221220 \u00b0C (long-term), 4 \u00b0C (short-term, up to 4 weeks)<\/td>\n<\/tr>\n
Sterility<\/td>\nThis product is not sterile\u2014it is not intended for injection or human use<\/td>\n<\/tr>\n
Intended Use<\/td>\nFor scientific research purposes only<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t
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Frequently Asked Questions About Selanka (FAQ)<\/h2>\n
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